{"id":19038,"date":"2021-03-29T11:27:33","date_gmt":"2021-03-29T03:27:33","guid":{"rendered":"http:\/\/www.flowtechsh.com\/?p=19038"},"modified":"2021-03-29T11:27:38","modified_gmt":"2021-03-29T03:27:38","slug":"%e7%b4%ab%e5%a4%96%e5%85%89%e8%be%85%e5%8a%a9%e7%94%b5%e5%8c%96%e5%ad%a6%e6%b0%a7%e5%8c%96%e5%8e%bb%e9%99%a4%e6%b1%a1%e6%b0%b4%e4%b8%ad%e7%9a%84%e6%8a%97%e6%80%a7%e7%bb%86%e8%8f%8c%e4%b8%8e%e5%9f%ba","status":"publish","type":"post","link":"https:\/\/www.flowtechsh.com\/archives\/19038.html","title":{"rendered":"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0"},"content":{"rendered":"\n<p>\u6297\u751f\u7d20\u7684\u6ee5\u7528\u53ef\u63d0\u9ad8\u548c\u52a0\u901f\u5fae\u751f\u7269\u7684\u6297\u751f\u7d20\u6297\u6027\u3002\u7531\u4e8e\u5728\u8fc7\u53bb\u7684\u534a\u4e2a\u4e16\u7eaa\u4e2d\uff0c\u5fae\u751f\u7269\u6297\u751f\u7d20\u6297\u6027\u7684\u589e\u957f\u901f\u7387\u8fdc\u8fdc\u8d85\u8fc7\u65b0\u578b\u6297\u751f\u7d20\u7684\u53d1\u73b0\u4e0e\u53d1\u660e\u901f\u5ea6\uff0c\u6297\u751f\u7d20\u6297\u6027\u5df2\u6210\u4e3a\u4e86\u5168\u7403\u6027\u7684\u5065\u5eb7\u98ce\u9669\u95ee\u9898\u5e76\u53d7\u5230\u5e7f\u6cdb\u5173\u6ce8\u3002\u636e\u4f30\u8ba1\uff0c\u5168\u7403\u6bcf\u5e74\u7ea6\u670970\u4e07\u6b7b\u4ea1\u75c5\u4f8b\u53ef\u5f52\u548e\u4e8e\u8010\u836f\u5fae\u751f\u7269\u611f\u67d3\u3002\u5982\u679c\u4e0d\u91c7\u53d6\u4efb\u4f55\u63aa\u65bd\uff0c\u81f32050\u5e74\uff0c\u8fd9\u4e00\u6b7b\u4ea1\u4eba\u6570\u4f1a\u8fdb\u4e00\u6b65\u589e\u957f\u81f3\u6bcf\u5e741000\u4e07\u4f8b\u3002\u5df2\u6709\u7814\u7a76\u8868\u660e\uff0c\u4f20\u7edf\u6c61\u6c34\u5904\u7406\u5de5\u827a\u65e0\u6cd5\u6709\u6548\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u751f\u7d20\u6297\u6027\u7ec6\u83cc(antibiotic resistant bacteria, arb)\u548c\u6297\u6027\u57fa\u56e0(antibiotic resistance genes, args)\u3002\u4e0d\u4ec5\u5982\u6b64\uff0c\u6c34\u5904\u7406\u8fc7\u7a0b\u4e2d\u672a\u88ab\u5b8c\u5168\u53bb\u9664\u7684\u6297\u751f\u7d20\u4ee5\u53ca\u5176\u4ed6\u5316\u5b66\u7269\u8d28(\u6bd4\u5982\u5176\u4ed6\u836f\u7269\u548c\u91cd\u91d1\u5c5e\u7b49)\u4f1a\u4fc3\u8fdb\u6297\u6027\u57fa\u56e0\u518d\u6c61\u6c34\u5904\u7406\u8bbe\u65bd\u4e2d\u7684\u6c34\u5e73\u8f6c\u79fb\uff0c\u4f7f\u5fae\u751f\u7269\u53ef\u4ee5\u4ece\u5468\u56f4\u73af\u5883\u4e2d(\u6bd4\u5982\u6c61\u6c34\u5904\u7406\u8bbe\u65bd\u4e2d\u7684\u4e0d\u540c\u5904\u7406\u5355\u5143)\u6444\u53d6\u6e38\u79bb\u7684\u6297\u6027\u57fa\u56e0\u4ece\u800c\u83b7\u5f97\u6297\u751f\u7d20\u6297\u6027\u3002<\/p>\n\n\n\n<p>\u4e3a\u4e86\u89e3\u51b3\u4e0a\u8ff0\u95ee\u9898\uff0c\u52a0\u5dde\u7406\u5de5\u5b66\u9662hoffmann\u6559\u6388\u7814\u7a76\u7ec4\u548c\u514b\u62c9\u514b\u68ee\u5927\u5b66\u6768\u9633\u6559\u6388\u7814\u7a76\u7ec4\u7ed3\u5408\u7d2b\u5916\u5149\u548c\u9ad8\u7ea7\u6c27\u5316\u6d88\u6bd2\u7684\u539f\u7406\uff0c\u5f00\u53d1\u4e86\u4e00\u79cd\u57fa\u4e8e\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1(blue tio2nanotube arrays, bntas)\u6750\u6599\u7684\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316(uv-assisted electrochemical oxidation, uv-eo)\u5de5\u827a\uff0c\u7528\u4e8e\u6df1\u5ea6\u53bb\u9664\u6c61\u6c34\u4e2darb\u53caargs\u3002\u5728\u8be5\u5c0f\u8bd5\u7814\u7a76\u4e2d\uff0c\u4e24\u79cdargs-\u56db\u73af\u7d20\u548c\u78fa\u80fa\u7532\u6076\u5511\u6297\u6027\u57fa\u56e0(teta\u548csul1)\uff0c\u4ee5\u53ca\u88ab\u5b83\u4eec\u5206\u522b\u8f6c\u5316\u7684\u8010\u56db\u73af\u7d20(tetracycline)\u548c\u8010\u78fa\u80fa\u7532\u6076\u5511(sulfamethoxazole)\u5927\u80a0\u6746\u83cc(escherichia coli, e. coli)\u7ecf\u7531uv-eo\u5904\u7406\u540e\u5206\u522b\u7531qpcr\u548c\u9009\u62e9\u6027\u743c\u8102\u57f9\u517b\u57fa\u8fdb\u884c\u5b9a\u91cf\u5206\u6790\u3002\u4e0e\u5355\u4e00\u7d2b\u5916\u5149\u6d88\u6bd2\u76f8\u6bd4\uff0cuv-eo\u6709\u6548\u589e\u5f3a\u4e86arb\u548cargs\u7684\u53bb\u9664\u6548\u7387\u3002\u5176\u4e2d\uff0c\u7531\u7535\u5316\u5b66\u6c27\u5316\u6c2f\u79bb\u5b50 (cl-)\u751f\u6210\u7684\u81ea\u7531\u6c2f\u4ee5\u53ca\u968f\u540e\u53d1\u751f\u7684\u7d2b\u5916\u5149\u548c\u6c2f\u7684\u5149\u50ac\u5316\u53cd\u5e94\u4f7f\u5f97\u53bb\u9664\u6548\u7387\u88ab\u8fdb\u4e00\u6b65\u63d0\u9ad8\u3002\u5728cl-\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0cuv-eo(uv-eo\/cl-)\u57fa\u4e8e\u5149\u901a\u91cf\u7684\u4e00\u7ea7\u52a8\u529b\u5b66\u901f\u7387\u5e38\u6570\u5bf9\u957f\u9776\u548c\u77ed\u9776\u5e8f\u5217\u5206\u522b\u4e3a\u5355\u4e00\u7d2b\u5916\u5149\u8f90\u7167\u53cd\u5e94\u4e0b\u7684 2.1-2.3\u548c1.3-1.8\u500d\u3002\u901a\u8fc7\u51dd\u80f6\u7535\u6cf3\u548c\u52a8\u529b\u5b66\u6a21\u578b\u8ba1\u7b97\uff0c\u6211\u4eec\u8fdb\u4e00\u6b65\u89e3\u6790\u4e86\u8d28\u7c92dna\u88ab\u4e0d\u540c\u81ea\u7531\u57fa\u7834\u574f\u7684\u53cd\u5e94\u673a\u7406\u3002\u6700\u540e\u6211\u4eec\u8bc1\u660e\u4e86uv-eo\u53ef\u4ee5\u6709\u6548\u5730\u6d88\u9664\u5395\u6240\u5e9f\u6c34\u4e2d\u7684arb\u548cargs\uff0c\u5c3d\u7ba1\u53cd\u5e94\u901f\u7387\u7565\u4f4e\u4e8e\u6a21\u62df\u5e9f\u6c34\u5b9e\u9a8c\u89c2\u6d4b\u503c\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"682\" height=\"348\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260652402363192630833.png\" alt=\"\" class=\"wp-image-19042\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c1\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c1\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260652402363192630833.png 682w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260652402363192630833-150x77.png 150w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260652402363192630833-300x153.png 300w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe1\uff1a\u7d2b\u5916\u5149\u5149\u7535\u50ac\u5316\u53bb\u9664\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0\u7814\u7a76\u7684\u5b9e\u9a8c\u65b9\u6848<\/p>\n\n\n\n<p>uv-eo\u5b9e\u9a8c\u5728\u53ef\u63a5\u6536\u4fa7\u5411uv\u8f90\u7167\u7684\u5149\u53cd\u5e94\u5668\u4e2d\u8fdb\u884c\u3002\u6211\u4eec\u4f7f\u7528\u4e86bnta\u548c\u94c2\u7f51\u5206\u522b\u4f5c\u4e3a\u9633\u6781\u548c\u9634\u6781\u7535\u6781\uff0c\u4f7f\u7528\u6ce2\u957f\u4e3a254 nm\u7684\u7d2b\u5916\u5149(uv254)\u4e3a\u7d2b\u5916\u5149\u6e90\u3002\u4f7f\u7528\u7898\u5316\u94be\u4f5c\u4e3a\u5316\u5b66\u9732\u5149\u8ba1\u6d4b\u5f97\u7684\u53cd\u5e94\u6c60\u5185\u7684uv254\u8f90\u7167\u5f3a\u5ea6\u4e3a5.0+0.1 mw\/cm2\u3002\u6211\u4eec\u5728\u5395\u6240\u5e9f\u6c34\u4e2d\u68c0\u51fa\u8f83\u9ad8\u6d53\u5ea6\u7684\u4e24\u79cdargs-teta\u548csul1\u3002\u56e0\u6b64\u5b83\u4eec\u88ab\u9009\u4e3a\u672c\u7814\u7a76\u4e2d\u7684\u76ee\u6807\u57fa\u56e0\u3002\u5982\u56fe1\u6240\u793a\uff0c\u6211\u4eec\u8bbe\u8ba1\u4e86\u7279\u5b9a\u7684\u5f15\u7269\u5e76\u501f\u52a9pcr\u6269\u589e\u6280\u672f\u83b7\u5f97\u4e86\u4e24\u79cd\u76ee\u6807args\u7684\u5168\u957f\u5e8f\u5217\u3002\u8fd9\u4e9b\u5e8f\u5217\u88ab\u5206\u522b\u514b\u9686\u8fdb\u8f7d\u4f53\u8d28\u7c92\u4e2d\u7ec4\u88c5\u4e3a\u5206\u522b\u542b\u6709teta\u548csul1\u7684\u65b0\u8f7d\u4f53\u8d28\u7c92- peb1-teta\u548cpeb1-sul1\u3002\u7f16\u8f91\u540e\u7684\u8f7d\u4f53\u8d28\u7c92\u901a\u8fc7\u8109\u51b2\u7535\u7a7f\u5b54\u6280\u672f\u8f6c\u79fb\u81f3\u611f\u53d7\u6001\u7ec6\u80dee. colimegax dh10b t1r\uff0c\u8fdb\u800c\u83b7\u5f97\u5206\u522b\u5177\u6709\u56db\u73af\u7d20\u548c\u78fa\u80fa\u7532\u6076\u5511\u6297\u6027\u7684\u5927\u80a0\u6746\u83cc\u7ec6\u80de\u3002\u6211\u4eec\u7814\u7a76\u4e86\u7ec6\u80de\u5185args(intracellular args, i-args)\u548c\u7ec6\u80de\u5916args(extracellular args, e-args)\u5728\u4e09\u79cd\u4e0d\u540c\u5904\u7406\u6761\u4ef6(uv254\u3001uv-eo\u4ee5\u53cauv-eo\/cl-)\u4e0b\u7684\u53bb\u9664\u6548\u679c\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"688\" height=\"230\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260653906177847804911.png\" alt=\"\" class=\"wp-image-19043\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c2\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c2\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260653906177847804911.png 688w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260653906177847804911-150x50.png 150w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260653906177847804911-300x100.png 300w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe2\uff1a\u7535\u6781\u7684\u5bfc\u5e26\u3001\u4ef7\u5e26\u548c\u8d39\u7c73\u80fd\u7ea7\u793a\u610f\u56fe(a)\u4e8c\u6c27\u5316\u949b\u7eb3\u7c73\u7ba1\uff0c(b)\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1\u4ee5\u53ca(c)\u7d2b\u5916\u5149\u8f90\u7167\u4e0b\u7684\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1<\/p>\n\n\n\n<p>\u6211\u4eec\u9009\u7528\u84dd\u8272\u7eb3\u7c73\u7ba1(bntas)\u4f5c\u4e3a\u7535\u6781\u6750\u6599\u3002\u5728\u6b64\u524d\u7684\u7cfb\u5217\u5de5\u4f5c\u4e2d(10.1021\/acscatal.7b04340\uff1b10.1021\/acs.est.6b03540)\uff0c\u6211\u4eec\u62a5\u9053\u4e86\u84dd\u8272\u7eb3\u7c73\u7ba1\u72ec\u7279\u7684\u5149\u7535\u7279\u6027\u3002bntas \u7279\u6709\u7684ti3+\u63ba\u6742\u6001\u8d4b\u4e88\u5176\u4f18\u79c0\u7684\u5bfc\u7535\u80fd\u529b\u3002\u8fd9\u4e2a\u7269\u7406\u73b0\u8c61\u76f4\u89c2\u8868\u73b0\u4e3a\u8d39\u7c73\u80fd\u7ea7\u4e0a\u79fb\u81f3\u5bfc\u5e26(\u56fe2a \u81f3b)\u3002\u6b64\u65f6\u5728\u5408\u9002\u7684\u9633\u6781\u7535\u4f4d\u4e0b\uff0c\u5916\u754c\u7535\u5b50\u53ef\u4ee5\u901a\u8fc7\u96a7\u7a7f\u6548\u5e94\u6ce8\u5165\u5bfc\u5e26\uff0c\u4fc3\u6210\u7535\u5316\u5b66\u6c27\u5316\u53cd\u5e94(\u56fe2b)\u3002\u672c\u7814\u7a76\u53d1\u73b0\uff0c\u826f\u597d\u5bfc\u7535\u7684bntas\u4ecd\u4fdd\u6709\u534a\u5bfc\u4f53\u6750\u6599\u7684\u6027\u8d28\u3002\u5728\u7d2b\u5916\u5149\u8f90\u7167\u4e0b\uff0c\u5149\u751f\u7535\u5b50\u53ef\u4ee5\u7a33\u5b9ati3+\u63ba\u6742\u6001\u3001\u63d0\u9ad8\u6750\u6599\u5728\u9ad8\u9633\u6781\u7535\u4f4d\u4e0b\u7684\u7a33\u5b9a\u6027\u3002\u540c\u65f6\u5149\u751f\u7a7a\u7a74(h+)\u53ef\u4ee5\u901a\u8fc7\u5149\u50ac\u5316\u8def\u5f84\u4ea7\u751f\u66f4\u591a\u7684\u81ea\u7531\u57fa\u548c\u6c27\u5316\u5242\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"412\" height=\"292\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260655570413109219964.png\" alt=\"\" class=\"wp-image-19044\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c3\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c3\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260655570413109219964.png 412w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260655570413109219964-150x106.png 150w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260655570413109219964-300x213.png 300w\" sizes=\"(max-width: 412px) 85vw, 412px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe3\uff1a\u4e0d\u540c\u53cd\u5e94\u6761\u4ef6\u4e0b\u82ef\u7532\u9178\u63a2\u9488\u5206\u5b50\u7684\u964d\u89e3\u52a8\u529b\u5b66\u53ca\u6a21\u578b\u62df\u5408\u7ed3\u679c<\/p>\n\n\n\n<p>\u7531\u4e8e\u82ef\u7532\u9178 (benzoic acid, ba)\u53ef\u4e0e\u591a\u79cd\u81ea\u7531\u57fa\u53cd\u5e94\u7684\u7279\u6027\uff0c\u6211\u4eec\u4f7f\u7528ba\u4f5c\u4e3a\u63a2\u9488\u5206\u5b50\u95f4\u63a5\u5b9a\u91cf\u5206\u6790\u4e86\u81ea\u7531\u57fa\u7684\u4ea7\u91cf\u3002\u901a\u8fc7\u52a8\u529b\u5b66\u6a21\u578b\u6a21\u62df\uff0c\u6211\u4eec\u8fdb\u4e00\u6b65\u4f30\u7b97\u4e86\u591a\u79cd\u81ea\u7531\u57fa(\u2022oh\u3001 cl\u2022\u3001 cl2\u2022-\u3001 cloh\u2022-\u7b49)\u7684\u6d53\u5ea6\u3002\u5982\u56fe3\u6240\u793a\uff0c\u5b9e\u9a8c\u6570\u636e(\u70b9)\u80fd\u88ab\u52a8\u529b\u5b66\u6a21\u578b(\u865a\u7ebf)\u8f83\u597d\u5730\u62df\u5408\u3002\u7ed3\u5408\u5b9e\u9a8c\u89c2\u6d4b\u548c\u6a21\u578b\u6a21\u62df\uff0c\u6211\u4eec\u53d1\u73b0\u5728\u6c2f\u79bb\u5b50\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0ccl2\u2022-\u3001cl\u2022\u548c\u2022oh\u662feo\u53cd\u5e94\u4e2d\u4e3b\u8981\u7684\u81ea\u7531\u57fa\u7269\u79cd\u3002\u7d2b\u5916\u8f90\u7167\u80fd\u591f\u901a\u8fc7\u5747\u76f8\u5149\u5316\u5b66\u53cd\u5e94(\u6e38\u79bb\u6c2f\u5149\u89e3)\u548c\u5f02\u76f8\u50ac\u5316\u53cd\u5e94(\u5149\u751f\u7a7a\u7a74\u6c27\u5316)\u63d0\u9ad8eo \u8fc7\u7a0b\u7684\u81ea\u7531\u57fa\u7684\u4ea7\u7387\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"683\" height=\"412\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260657196997677151410.png\" alt=\"\" class=\"wp-image-19045\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c4\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c4\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260657196997677151410.png 683w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260657196997677151410-150x90.png 150w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260657196997677151410-300x181.png 300w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe4\uff1a\u4e0d\u540c\u6761\u4ef6\u4e0b\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1\u5bf9\u6297\u751f\u7d20\u6297\u6027\u5927\u80a0\u6746\u83cc\u548c\u6297\u6027\u57fa\u56e0\u7684\u53bb\u9664\u52a8\u529b\u5b66<\/p>\n\n\n\n<p>\u6211\u4eec\u8fdb\u4e00\u6b65\u6d4b\u8bd5\u4e86\u6297\u751f\u7d20\u6297\u6027\u5927\u80a0\u6746\u83cc\u5728\u4e09\u79cd\u4e0d\u540c\u53cd\u5e94\u6761\u4ef6\u4e0b(\u5355\u4e00uv254\u3001uv-eo\/\u4ee5\u53cauv-eo\/cl-)\u7684\u53bb\u9664\u6548\u679c(\u5982\u56fe4\u6240\u793a)\u3002\u6211\u4eec\u53d1\u73b0\u53bb\u9664args\u6bd4\u6740\u706darb\u66f4\u5177\u6709\u6311\u6218\u6027\u3002\u8fd9\u53ef\u80fd\u56e0\u4e3a\u9664\u4e86arg\u7247\u6bb5\u5916\uff0carb\u7ec6\u80de\u4e2d\u7684\u5168\u57fa\u56e0\u7ec4dna\u5e8f\u5217\u4e2d\u8fd8\u6709\u66f4\u591a\u7684\u201c\u751f\u6b7b\u6538\u5173\u201d\u7684\u9776\u70b9\u3002\u6b64\u5916\u81ea\u7531\u57fa\u4e5f\u53ef\u4ee5\u901a\u8fc7\u7834\u574f\u7ec6\u80de\u5176\u4ed6\u7ed3\u6784(\u7ec6\u80de\u58c1)\u8fbe\u5230\u706d\u6d3b\u7684\u76ee\u7684\u3002\u8fd9\u4e2a\u7ed3\u679c\u8fdb\u4e00\u6b65\u5370\u8bc1\u4e86\u524d\u4eba\u7814\u7a76\u4e2d\u7684\u7ed3\u8bba\uff0c\u5373args\u53ef\u4ee5\u5728\u5373\u4f7f\u5bbf\u4e3barb\u88ab\u706d\u6d3b\u7684\u60c5\u51b5\u4e0b\u5e78\u5b58\uff0c\u4ece\u800c\u7ee7\u7eed\u901a\u8fc7\u57fa\u56e0\u7684\u6c34\u5e73\u8f6c\u79fb\u4f20\u64ad\u6297\u751f\u7d20\u6297\u6027\u3002\u6211\u4eec\u7684\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u4e0e\u5355\u4e00uv254\u5de5\u827a\u76f8\u6bd4, uv\/eo\u53ef\u501f\u52a9\u81ea\u7531\u57fa\u6c27\u5316\u53cd\u5e94\u63d0\u9ad8arb\u548cargs\u7684\u53bb\u9664\u6548\u7387\u3002\u4e09\u79cd\u4e0d\u540c\u6761\u4ef6\u4e0barb\u548cargs\u7684\u53bb\u9664\u6548\u7387\u7531\u9ad8\u5230\u4f4e\u7684\u987a\u5e8f\u4e3a\uff1auv-eo\/cl-> uv-eo > uv \u3002\u5bf9\u4e0a\u8ff0\u53cd\u5e94\u6761\u4ef6\u4e0b\u957f\u9776\u548c\u77ed\u9776\u5e8f\u5217\u7684\u964d\u89e3\u66f2\u7ebf\u5728\u7b26\u5408\u4e00\u7ea7\u591a\u529b\u5b66\u7684\u8303\u56f4\u5185\u5206\u522b\u8fdb\u884c\u4e00\u7ea7\u52a8\u529b\u5b66\u62df\u5408\uff0c\u7531\u6b64\u53ef\u5f97\u57fa\u4e8e\u5149\u901a\u91cf\u7684\u4e00\u7ea7\u52a8\u529b\u5b66\u5e38\u6570\u3002\u7ed3\u679c\u8868\u660e\u4e0e\u5355\u4e00uv254\u76f8\u6bd4\uff0cuv-eo\u53ef\u5c06args\u957f\u9776\u548c\u77ed\u9776\u5e8f\u5217\u7684\u964d\u89e3\u901f\u7387\u5206\u522b\u63d0\u9ad8\u81f31.5-1.6\u548c1.1-1.3\u500d\u3002\u5f15\u5165cl-\u53ef\u5c06\u5176\u964d\u89e3\u901f\u7387\u8fdb\u4e00\u6b65\u5206\u522b\u63d0\u9ad8\u81f32.1-2.3\u548c1.3-1.8\u500d\u3002\u957f\u9776\u5e8f\u5217\u7531\u4e8e\u542b\u6709\u66f4\u591a\u7684\u653b\u51fb\u70b9\u4f4d\uff0c\u5176\u964d\u89e3\u901f\u7387\u663e\u8457\u9ad8\u4e8e\u77ed\u9776\u5e8f\u5217\u3002\u6b64\u5916\uff0c\u5bf9\u4e8e\u540c\u4e00\u9776\u5e8f\u5217\uff0ce-args\u7684\u964d\u89e3\u901f\u7387\u666e\u904d\u9ad8\u4e8ei-args\uff0c\u9664\u4e86\u4e00\u7ec4teta-short\u5728\u5355\u4e00uv254\u8f90\u7167\u4e0b\u7684\u964d\u89e3\u5b9e\u9a8c\u4e2de-args\u4e0ei-args\u964d\u89e3\u901f\u7387\u5e76\u65e0\u663e\u8457\u4e0d\u540c\u4e4b\u5916\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"401\" height=\"574\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260659596640729019275.png\" alt=\"\" class=\"wp-image-19046\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c5\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c5\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260659596640729019275.png 401w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260659596640729019275-105x150.png 105w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260659596640729019275-210x300.png 210w\" sizes=\"(max-width: 401px) 85vw, 401px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe5\uff1a\u4e0d\u540c\u53bb\u9664\u6761\u4ef6\u4e0b\u542b\u6297\u6027\u57fa\u56e0\u7684\u8d28\u7c92dna\u968f\u65f6\u95f4\u53d8\u5316\u7684\u51dd\u80f6\u7535\u6cf3\u56fe<\/p>\n\n\n\n<p>\u5bf9\u4e0a\u6587\u63d0\u5230\u7684\u7ecf\u4e09\u79cd\u4e0d\u540c\u6761\u4ef6\u4e0b\u5904\u7406\u4e86\u4e0d\u540c\u65f6\u95f4\u7684\u8d28\u7c92peb1-sul1\u8fdb\u884c\u51dd\u80f6\u7535\u6cf3\u6d4b\u8bd5(\u5982\u56fe5)\u3002\u7ed3\u679c\u8868\u660e\uff0c\u5728\u8f83\u4f4e\u5242\u91cf\u7684uv254\u8f90\u7167\u4e0b\uff0c\u8d28\u7c92\u4e3b\u8981\u53d1\u751f\u78b1\u57fa\u5bf9\u7684\u6539\u53d8\u3002\u53ea\u6709\u5728\u8db3\u591f\u9ad8\u5242\u91cf(> 1.5 j\/cm2)\u7684\u5355\u4e00uv254\u8f90\u7167\u4e0b\uff0c\u8d28\u7c92\u624d\u4f1a\u53d1\u751f\u5f62\u6001\u53d8\u5316\u3002\u800cuv-eo\u663e\u8457\u52a0\u901f\u4e86\u8d28\u7c92\u7684\u5f62\u6001\u53d8\u5316\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"686\" height=\"414\" src=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260661008443068108096.png\" alt=\"\" class=\"wp-image-19047\"\/ alt=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c6\u5f20\" title=\"\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316\u53bb\u9664\u6c61\u6c34\u4e2d\u7684\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0 \u65b0\u95fb\u8d44\u8baf \u7b2c6\u5f20-\" srcset=\"https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260661008443068108096.png 686w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260661008443068108096-150x91.png 150w, https:\/\/www.flowtechsh.com\/wp-content\/uploads\/2021\/03\/6375260661008443068108096-300x181.png 300w\" sizes=\"(max-width: 709px) 85vw, (max-width: 909px) 67vw, (max-width: 984px) 61vw, (max-width: 1362px) 45vw, 600px\" \/><\/figure><\/div>\n\n\n\n<p style=\"text-align:center\">\u56fe6\uff1a\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1-\u7d2b\u5916\u5149\u5149\u7535\u50ac\u5316\u5bf9\u5395\u6240\u5e9f\u6c34\u4e2d\u539f\u59cb\u7ec6\u83cc\u548c\u6297\u6027\u57fa\u56e0\u7684\u53bb\u9664<\/p>\n\n\n\n<p>\u6700\u540e\uff0c\u6211\u4eec\u6d4b\u8bd5\u4e86uv-eo \u5de5\u827a\u7684\u5bf9\u5395\u6240\u5e9f\u6c34\u4e2d\u7ec6\u83cc\u548cargs\u7684\u5904\u7406\u6548\u679c(\u5982\u56fe6)\u3002\u5b9e\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u5728300 mj\/cm2\u7684uv254\u8f90\u7167\u5242\u91cf\u4e0b\uff0c\u5e9f\u6c34\u4e2d\u7684\u7ec6\u83cc\u7684\u53bb\u9664\u7387\u8fbe\u52302.7-log10\u3002\u5728600 mj\/cm2\u7684uv254\u8f90\u7167\u5242\u91cf\u4e0b\uff0c\u4e24\u4e2a\u957f\u9776\u5e8f\u5217teta-long\u548csul1-long\u7684\u53bb\u9664\u7387\u5206\u522b\u8fbe\u52301.1-log10\u548c2.9-log10\uff0c\u800c\u4e24\u4e2a\u77ed\u9776\u5e8f\u5217\u53bb\u9664\u7387\u63a5\u8fd12-log10\u3002uv-eo\u5bf9\u5e9f\u6c34\u4e2dargs\u7684\u5904\u7406\u6548\u7387\u4f4e\u4e8e\u6a21\u62df\u5e9f\u6c34\u5904\u7406\u7ed3\u679c\u3002\u539f\u56e0\u53ef\u80fd\u5305\u62ec1)\u81ea\u7531\u57fa\u548c\u6e38\u79bb\u6c2f\u88ab\u5e9f\u6c34\u4e2d\u5176\u4ed6\u5316\u5408\u7269(\u6bd4\u5982\u6c28\u6c2e\u548c\u6709\u673a\u7269)\u6d88\u8017\uff1b2)\u7d2b\u5916\u5149\u88ab\u5e9f\u6c34\u4e2d\u5176\u4ed6\u6c61\u67d3\u7269\u5438\u6536\uff1b3)\u5e9f\u6c34\u4e2d\u7ec6\u83cc\u53caargs\u6d53\u5ea6\u8fdc\u4f4e\u4e8e\u6a21\u62df\u5e9f\u6c34\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u6211\u4eec\u53d1\u73b0uv-eo 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resistant bacteria, arb)\u548c\u6297\u6027\u57fa\u56e0(antibiotic resistance genes, args)\u3002\u4e0d\u4ec5\u5982\u6b64\uff0c\u6c34\u5904\u7406\u8fc7\u7a0b\u4e2d\u672a\u88ab\u5b8c\u5168\u53bb\u9664\u7684\u6297\u751f\u7d20\u4ee5\u53ca\u5176\u4ed6\u5316\u5b66\u7269\u8d28(\u6bd4\u5982\u5176\u4ed6\u836f\u7269\u548c\u91cd\u91d1\u5c5e\u7b49)\u4f1a\u4fc3\u8fdb\u6297\u6027\u57fa\u56e0\u518d\u6c61\u6c34\u5904\u7406\u8bbe\u65bd\u4e2d\u7684\u6c34\u5e73\u8f6c\u79fb\uff0c\u4f7f\u5fae\u751f\u7269\u53ef\u4ee5\u4ece\u5468\u56f4\u73af\u5883\u4e2d(\u6bd4\u5982\u6c61\u6c34\u5904\u7406\u8bbe\u65bd\u4e2d\u7684\u4e0d\u540c\u5904\u7406\u5355\u5143)\u6444\u53d6\u6e38\u79bb\u7684\u6297\u6027\u57fa\u56e0\u4ece\u800c\u83b7\u5f97\u6297\u751f\u7d20\u6297\u6027\u3002 \u4e3a\u4e86\u89e3\u51b3\u4e0a\u8ff0\u95ee\u9898\uff0c\u52a0\u5dde\u7406\u5de5\u5b66\u9662hoffmann\u6559\u6388\u7814\u7a76\u7ec4\u548c\u514b\u62c9\u514b\u68ee\u5927\u5b66\u6768\u9633\u6559\u6388\u7814\u7a76\u7ec4\u7ed3\u5408\u7d2b\u5916\u5149\u548c\u9ad8\u7ea7\u6c27\u5316\u6d88\u6bd2\u7684\u539f\u7406\uff0c\u5f00\u53d1\u4e86\u4e00\u79cd\u57fa\u4e8e\u4e8c\u6c27\u5316\u949b\u84dd\u8272\u7eb3\u7c73\u7ba1(blue tio2nanotube arrays, bntas)\u6750\u6599\u7684\u7d2b\u5916\u5149\u8f85\u52a9\u7535\u5316\u5b66\u6c27\u5316(uv-assisted electrochemical oxidation, uv-eo)\u5de5\u827a\uff0c\u7528\u4e8e\u6df1\u5ea6\u53bb\u9664\u6c61\u6c34\u4e2darb\u53caargs\u3002\u5728\u8be5\u5c0f\u8bd5\u7814\u7a76\u4e2d\uff0c\u4e24\u79cdargs-\u56db\u73af\u7d20\u548c\u78fa\u80fa\u7532\u6076\u5511\u6297\u6027\u57fa\u56e0(teta\u548csul1)\uff0c\u4ee5\u53ca\u88ab\u5b83\u4eec\u5206\u522b\u8f6c\u5316\u7684\u8010\u56db\u73af\u7d20(tetracycline)\u548c\u8010\u78fa\u80fa\u7532\u6076\u5511(sulfamethoxazole)\u5927\u80a0\u6746\u83cc(escherichia coli, e. coli)\u7ecf\u7531uv-eo\u5904\u7406\u540e\u5206\u522b\u7531qpcr\u548c\u9009\u62e9\u6027\u743c\u8102\u57f9\u517b\u57fa\u8fdb\u884c\u5b9a\u91cf\u5206\u6790\u3002\u4e0e\u5355\u4e00\u7d2b\u5916\u5149\u6d88\u6bd2\u76f8\u6bd4\uff0cuv-eo\u6709\u6548\u589e\u5f3a\u4e86arb\u548cargs\u7684\u53bb\u9664\u6548\u7387\u3002\u5176\u4e2d\uff0c\u7531\u7535\u5316\u5b66\u6c27\u5316\u6c2f\u79bb\u5b50 (cl-)\u751f\u6210\u7684\u81ea\u7531\u6c2f\u4ee5\u53ca\u968f\u540e\u53d1\u751f\u7684\u7d2b\u5916\u5149\u548c\u6c2f\u7684\u5149\u50ac\u5316\u53cd\u5e94\u4f7f\u5f97\u53bb\u9664\u6548\u7387\u88ab\u8fdb\u4e00\u6b65\u63d0\u9ad8\u3002\u5728cl-\u5b58\u5728\u7684\u6761\u4ef6\u4e0b\uff0cuv-eo(uv-eo\/cl-)\u57fa\u4e8e\u5149\u901a\u91cf\u7684\u4e00\u7ea7\u52a8\u529b\u5b66\u901f\u7387\u5e38\u6570\u5bf9\u957f\u9776\u548c\u77ed\u9776\u5e8f\u5217\u5206\u522b\u4e3a\u5355\u4e00\u7d2b\u5916\u5149\u8f90\u7167\u53cd\u5e94\u4e0b\u7684 2.1-2.3\u548c1.3-1.8\u500d\u3002\u901a\u8fc7\u51dd\u80f6\u7535\u6cf3\u548c\u52a8\u529b\u5b66\u6a21\u578b\u8ba1\u7b97\uff0c\u6211\u4eec\u8fdb\u4e00\u6b65\u89e3\u6790\u4e86\u8d28\u7c92dna\u88ab\u4e0d\u540c\u81ea\u7531\u57fa\u7834\u574f\u7684\u53cd\u5e94\u673a\u7406\u3002\u6700\u540e\u6211\u4eec\u8bc1\u660e\u4e86uv-eo\u53ef\u4ee5\u6709\u6548\u5730\u6d88\u9664\u5395\u6240\u5e9f\u6c34\u4e2d\u7684arb\u548cargs\uff0c\u5c3d\u7ba1\u53cd\u5e94\u901f\u7387\u7565\u4f4e\u4e8e\u6a21\u62df\u5e9f\u6c34\u5b9e\u9a8c\u89c2\u6d4b\u503c\u3002 \u56fe1\uff1a\u7d2b\u5916\u5149\u5149\u7535\u50ac\u5316\u53bb\u9664\u6297\u6027\u7ec6\u83cc\u4e0e\u57fa\u56e0\u7814\u7a76\u7684\u5b9e\u9a8c\u65b9\u6848 uv-eo\u5b9e\u9a8c\u5728\u53ef\u63a5\u6536\u4fa7\u5411uv\u8f90\u7167\u7684\u5149\u53cd\u5e94\u5668\u4e2d\u8fdb\u884c\u3002\u6211\u4eec\u4f7f\u7528\u4e86bnta\u548c\u94c2\u7f51\u5206\u522b\u4f5c\u4e3a\u9633\u6781\u548c\u9634\u6781\u7535\u6781\uff0c\u4f7f\u7528\u6ce2\u957f\u4e3a254 nm\u7684\u7d2b\u5916\u5149(uv254)\u4e3a\u7d2b\u5916\u5149\u6e90\u3002\u4f7f\u7528\u7898\u5316\u94be\u4f5c\u4e3a\u5316\u5b66\u9732\u5149\u8ba1\u6d4b\u5f97\u7684\u53cd\u5e94\u6c60\u5185\u7684uv254\u8f90\u7167\u5f3a\u5ea6\u4e3a5.0+0.1 mw\/cm2\u3002\u6211\u4eec\u5728\u5395\u6240\u5e9f\u6c34\u4e2d\u68c0\u51fa\u8f83\u9ad8\u6d53\u5ea6\u7684\u4e24\u79cdargs-teta\u548csul1\u3002\u56e0\u6b64\u5b83\u4eec\u88ab\u9009\u4e3a\u672c\u7814\u7a76\u4e2d\u7684\u76ee\u6807\u57fa\u56e0\u3002\u5982\u56fe1\u6240\u793a\uff0c\u6211\u4eec\u8bbe\u8ba1\u4e86\u7279\u5b9a\u7684\u5f15\u7269\u5e76\u501f\u52a9pcr\u6269\u589e\u6280\u672f\u83b7\u5f97\u4e86\u4e24\u79cd\u76ee\u6807args\u7684\u5168\u957f\u5e8f\u5217\u3002\u8fd9\u4e9b\u5e8f\u5217\u88ab\u5206\u522b\u514b\u9686\u8fdb\u8f7d\u4f53\u8d28\u7c92\u4e2d\u7ec4\u88c5\u4e3a\u5206\u522b\u542b\u6709teta\u548csul1\u7684\u65b0\u8f7d\u4f53\u8d28\u7c92- 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